SCHEMBL5728040

SCHEMBL5728040

O=S(=O)(O)c1c(O)cccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
ALDH1A1 P00352 3/20 0.46
CXCR2 P25025 1/20 0.39
CX3CR1 P49238 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ATM Q13315 1/20 0.38
AURKA O14965 2/20 0.37
AURKB Q96GD4 2/20 0.37
CNR1 P21554 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALOX12 P18054 1/20 0.36
AKR1B1 P15121 1/20 0.36
GAA P10253 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440935 0.86 ALDH1A1 (0.44) TSHRALDH1A1KMT2AMEN1TDP1
Hydrochloric Acid SCHEMBL27552065 0.84 ALDH1A1 (0.42) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL582872 0.84 ALDH1A1 (0.43) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL5432881 0.81 AURKA (0.41) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL149755 0.80 TTR (0.44) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL19206145 0.80 CYP3A4 (0.41) TSHRALDH1A1CXCR2CX3CR1TDP1
SCHEMBL2844949 0.80 NSD2 (0.39) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL14395756 0.77 DPP4 (0.41) TSHRALDH1A1CXCR2CX3CR1ATM
SCHEMBL359454 0.77 AURKA (0.47) TSHRALDH1A1KMT2AMEN1TDP1
SCHEMBL4635992 0.77 SLC40A1 (0.43) ALDH1A1KMT2AMEN1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361399-A1 FLUORESCENT DYES WITH LARGE STOKES SHIFT ROCHE MOLECULAR SYSTEMS INC (US) 2025-11-27 US claimed
EP-4547757-A2 FLUORESCENT DYES WITH LARGE STOKES SHIFT F. Hoffmann-La Roche AG (CH) 2025-05-07 EP claimed
WO-2024002924-A2 FLUORESCENT DYES WITH LARGE STOKES SHIFT F. HOFFMANN-LA ROCHE AG (CH) 2024-01-04 WO claimed
WO-2015049343-A1 SYSTEM FOR THE DETECTION AND QUANTIFICATION OF A URANIUM ION UNIVERSITE DE LIMOGES (FR) 2015-04-09 WO claimed
US-3957660-A SULFONATED PHENOLS AS DISPERSANTS TEXACO INC. (US) 1976-05-18 US claimed
US-20250361399-A1 FLUORESCENT DYES WITH LARGE STOKES SHIFT ROCHE MOLECULAR SYSTEMS INC (US) 2025-11-27 US disclosed
WO-2025103220-A1 PYRIDYL ALKOXY PYRIMIDINE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-05-22 WO disclosed
EP-4547757-A2 FLUORESCENT DYES WITH LARGE STOKES SHIFT F. Hoffmann-La Roche AG (CH) 2025-05-07 EP disclosed
CN-110494443-B Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds and cell targeting molecules for site-specific conjugation 分子模板公司 2024-12-06 CN disclosed
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 CN disclosed
WO-2024002924-A2 FLUORESCENT DYES WITH LARGE STOKES SHIFT F. HOFFMANN-LA ROCHE AG (CH) 2024-01-04 WO disclosed
CN-114773439-A Shiga toxin A subunit effector polypeptides, shiga toxin effector scaffolds and cell targeting molecules for site-specific conjugation 分子模板公司 2022-07-22 CN disclosed
EP-1146062-A1 Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers Kaneka Corporation (JP) 2001-10-17 EP disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
EP-0095171-B1 COMPOSITION FOR CLEANING SURFACE OF SUBSTRATE Daikin Kogyo Co., Ltd. (JP) 1987-09-09 EP disclosed
EP-0218127-A1 Method and reagent for the specific determination of HDL-Cholesterol in serum Roche Diagnostics GmbH (DE) 1987-04-15 EP disclosed
US-4221674-A FOR DISSOLVING OF POLYMERIC SUBSTANCES ALLIED CHEMICAL CORPORATION (US) 1980-09-09 US disclosed
US-4215005-A ORGANIC SULFONIC ACID AND A HYDROGEN FLUORIDE COMPLEX WITH A NITROGEN CONTAINING COMPOUND ALLIED CHEMICAL CORPORATION (US) 1980-07-29 US disclosed
US-4165295-A PHOTORESISTS, ORGANIC SULFONIC ACIDS, FLUORIDE ION ALLIED CHEMICAL CORPORATION (US) 1979-08-21 US disclosed
US-3957660-A SULFONATED PHENOLS AS DISPERSANTS TEXACO INC. (US) 1976-05-18 US disclosed