Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 12/20 | 0.43 |
| ▸ | CES1 | P23141 | 7/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575032 | 0.98 | TSHR (0.41) | TSHRFAAHCES1TRPV1CES2 | |
| SCHEMBL13661862 | 0.83 | FAAH (0.48) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL18751671 | 0.83 | FAAH (0.48) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL12247043 | 0.83 | FAAH (0.48) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL19163900 | 0.83 | FAAH (0.48) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL16722811 | 0.83 | FAAH (0.48) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL16640758 | 0.83 | FAAH (0.48) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL3628936 | 0.81 | HPGD (0.35) | TSHRHIF1AKMT2A | |
| SCHEMBL16640759 | 0.81 | FAAH (0.46) | TSHRFAAHCES1CES2CYP1A2 | |
| SCHEMBL13196030 | 0.78 | FAAH (0.61) | FAAHCES1CES2CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514642-A | HERBICIDES FOR PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |
| US-5491123-A | Herbicides containing 3-aminobenzo(B)thiophenes as antidotes | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-13 | — | — | US | disclosed |