SCHEMBL8977751

SCHEMBL8977751

CC(=O)C(C)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.66
ALDH1A1 P00352 4/20 0.58
HTT P42858 3/20 0.58
NPC1 O15118 1/20 0.57
GAA P10253 1/20 0.55
KMT2A Q03164 1/20 0.55
TSHR P16473 2/20 0.54
POLB P06746 2/20 0.54
MAPT P10636 1/20 0.54
USP2 O75604 1/20 0.53
HPGD P15428 1/20 0.51
ALOX15 P16050 2/20 0.50
MAPK1 P28482 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TP53 P04637 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10577708 0.86 LMNA (0.68) LMNAALDH1A1HTTNPC1GAA
SCHEMBL125972 0.84 LMNA (0.71) LMNAALDH1A1HTTNPC1GAA
SCHEMBL29472125 0.84 LMNA (0.71) LMNAALDH1A1HTTNPC1GAA
SCHEMBL7399848 0.84 LMNA (0.71) LMNAALDH1A1HTTNPC1GAA
SCHEMBL478339 0.84 LMNA (0.71) LMNAALDH1A1HTTNPC1GAA
SCHEMBL5384717 0.82 LMNA (0.64) LMNAALDH1A1HTTNPC1GAA
SCHEMBL6099472 0.82 LMNA (0.69) LMNAALDH1A1HTTNPC1GAA
Hydrochloric Acid SCHEMBL7805764 0.82 LMNA (0.69) LMNAALDH1A1HTTNPC1GAA
SCHEMBL10354184 0.82 LMNA (0.64) LMNAALDH1A1HTTNPC1GAA
Hydrochloric Acid SCHEMBL6985664 0.82 LMNA (0.69) LMNAALDH1A1HTTNPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112341373-B Preparation method of ftibamzone 山东嘉成医药科技有限公司 2022-04-08 CN claimed
CN-112341373-A Preparation method of ftibamzone 山东嘉成医药科技有限公司 2021-02-09 CN claimed
CN-112341373-B Preparation method of ftibamzone 山东嘉成医药科技有限公司 2022-04-08 CN disclosed
CN-112341373-B Preparation method of ftibamzone 山东嘉成医药科技有限公司 2022-04-08 CN disclosed
CN-112341373-A Preparation method of ftibamzone 山东嘉成医药科技有限公司 2021-02-09 CN disclosed
CN-112341373-A Preparation method of ftibamzone 山东嘉成医药科技有限公司 2021-02-09 CN disclosed
CN-109988095-B Preparation method of 3-phthalimide-2-oxo-n-butyraldehyde bis-thiosemicarbazone 淮北师范大学 2020-06-30 CN disclosed
US-5510344-A Acrylate fungicides SCHERING AGROCHEMICALS LIMITED (GB) 1996-04-23 US disclosed
EP-0378308-B1 Acrylate fungicides AGREVO UK LTD (GB) 1996-04-10 EP disclosed
US-5332752-A Acrylate fungicides SCHERING AGROCHEMICALS LIMITED (GB) 1994-07-26 US disclosed
EP-0378308-A1 Acrylate fungicides AgrEvo UK Limited (GB) 1990-07-18 EP disclosed