Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399848 | 1.00 | LMNA (0.71) | LMNAGAAKDM4EKMT2ACASP1 | |
| SCHEMBL29472125 | 1.00 | LMNA (0.71) | LMNAGAAKDM4EKMT2ACASP1 | |
| SCHEMBL125972 | 1.00 | LMNA (0.71) | LMNAGAAKDM4EKMT2ACASP1 | |
| Hydrochloric Acid SCHEMBL6985664 | 0.98 | LMNA (0.69) | LMNAGAAKDM4EKMT2ACASP1 | |
| Hydrochloric Acid SCHEMBL7805764 | 0.98 | LMNA (0.69) | LMNAGAAKDM4EKMT2ACASP1 | |
| SCHEMBL10577708 | 0.86 | LMNA (0.68) | LMNAGAAKMT2AALDH1A1HTT | |
| SCHEMBL8977751 | 0.84 | LMNA (0.66) | LMNAGAAKMT2AALDH1A1HTT | |
| SCHEMBL31746155 | 0.84 | KDM4E (0.80) | LMNAGAAKDM4EKMT2ACASP1 | |
| SCHEMBL729029 | 0.83 | LMNA (1.00) | LMNAGAAKMT2AALDH1A1HTT | |
| SCHEMBL12022720 | 0.83 | LMNA (1.00) | LMNAGAAKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723425-B2 | Pigment compositions with modified ATRP copolymer dispersants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | claimed |
| EP-0596015-B1 | SUBSTITUTED BETA-LACTAM COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS AND PROCESSES FOR THE PREPARATION THEREOF | SCHERING CORP (US) | 1997-10-01 | — | — | EP | claimed |
| US-4360665-A | 4\"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor | ELI LILLY AND COMPANY (US) | 1982-11-23 | — | — | US | claimed |
| US-12612386-B2 | Heteroaryl-triazole compounds as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-04-28 | — | — | US | disclosed |
| US-12610949-B2 | Heteroaryl-triazole compounds as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-04-28 | — | — | US | disclosed |
| EP-4041393-B1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2026-04-08 | — | — | EP | disclosed |
| US-20260070945-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2026-03-12 | — | — | US | disclosed |
| US-12564583-B2 | Small molecules against cereblon to enhance effector T cell function | Lee Moffitt Cancer Center and Research Institute, Inc. (US) | 2026-03-03 | — | — | US | disclosed |
| US-20250250299-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2025-08-07 | — | — | US | disclosed |
| EP-3924349-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE ROSKAMP INST (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20250163104-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2025-05-22 | — | — | US | disclosed |
| US-4696930-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0233733-A2 | Process for producing N-phthaloyl-p-nitro-L-phenylalanine | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-26 | — | — | EP | disclosed |
| CN-85105066-A | The production of condensed seven-membered compounds, their and application | — | 1986-12-31 | — | — | CN | disclosed |
| EP-0198325-A2 | Substituted aniline derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1986-10-22 | — | — | EP | disclosed |
| US-4411905-A | Antisecretory 1,2,4-triazole-3-thiols | RICHARDSON-MERRELL INC. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4360665-A | 4\"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor | ELI LILLY AND COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |
| US-4230715-A | 1,2,4-Triazole-3-thiols as antisecretory agents | RICHARDSON-MERRELL INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-3994940-A | Preparation of 1-(2-(dimethylamino)ethyl)-6-phenyl-4H-5-triazolo(4,3-a)(1,4)benzodiazepines | THE UPJOHN COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12610949-B2 | Heteroaryl-triazole compounds as pesticides | CTRL, PTMS, DDT | LMNA 4346/4885GAA 3750/4885KDM4E 2954/4885 |
| US-12612386-B2 | Heteroaryl-triazole compounds as pesticides | CBR3, CYCS, HCN1 | LMNA 3022/4885GAA 4785/4885KDM4E 3487/4885 |
| US-20250163104-A1 | MACROCYCLIC IMMUNOMODULATORS | CD274, PDCD1LG2, PDCD1 | LMNA 4505/4885GAA 1725/4885KDM4E 1355/4885 |
| US-20260070945-A1 | MACROCYCLIC IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | LMNA 2037/4885GAA 3318/4885KDM4E 587/4885 |
| US-12564583-B2 | Small molecules against cereblon to enhance effector T cell function | CRBN, CD4, ICOS | LMNA 2916/4885GAA 3366/4885KDM4E 1961/4885 |
| US-20250250299-A1 | MACROCYCLIC IMMUNOMODULATORS | CD274, PDCD1LG2, PDCD1 | LMNA 4711/4885GAA 2185/4885KDM4E 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.