Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715740 | 0.81 | CCR1 (0.32) | — | |
| SCHEMBL8977848 | 0.76 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL8777264 | 0.76 | MAPK1 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL1315596 | 0.74 | MAPK1 (0.44) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL2440105 | 0.70 | CCR1 (0.40) | MEN1KMT2A | |
| SCHEMBL30382126 | 0.69 | HCRTR1 (0.42) | — | |
| SCHEMBL536688 | 0.69 | HCRTR1 (0.42) | — | |
| SCHEMBL930849 | 0.69 | KCNH2 (0.44) | MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL536855 | 0.68 | SYK (0.36) | MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL9248879 | 0.68 | ENPP2 (0.41) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559134-A | Leukotriene-B4 antagonists, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |