SCHEMBL8977839

SCHEMBL8977839

CC(C)(C)CCCCCCCCC(=O)NO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 9/20 0.65
HDAC1 Q13547 8/20 0.65
HDAC6 Q9UBN7 6/20 0.65
HDAC3 O15379 5/20 0.65
HDAC2 Q92769 5/20 0.65
HDAC5 Q9UQL6 3/20 0.65
HSP90AA1 P07900 1/20 0.59
HDAC11 Q96DB2 4/20 0.44
HDAC10 Q969S8 3/20 0.44
NCOR2 Q9Y618 3/20 0.44
ALDH1A1 P00352 1/20 0.44
HDAC4 P56524 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
ALOX5 P09917 1/20 0.43
KDM4E B2RXH2 1/20 0.43
BRD4 O60885 1/20 0.43
NCOR1 O75376 1/20 0.43
NR1I2 O75469 1/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977834 1.00 HDAC8 (0.65) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL14454660 0.98 HDAC1 (0.61) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL13024169 0.91 HDAC3 (0.56) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL3451176 0.83 HDAC8 (0.60) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL10253845 0.83 ALDH1A1 (0.44) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL195634 0.83 ALDH1A1 (0.44) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL3917890 0.83 ALDH1A1 (0.44) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL9520599 0.81 HDAC2 (0.52) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL9163443 0.81 ALDH1A1 (0.52) HDAC8HDAC1HDAC6HDAC3HDAC2
SCHEMBL14984414 0.81 ALDH1A1 (0.52) HDAC8HDAC1HDAC6HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598747-B1 N-ETHYL HYDROXAMIC ACID CHELANTS MET TECH SYSTEMS LTD (CA) 1996-04-24 EP claimed
US-5487842-A LOW VISCOSITY, RAPID PHASE SEPARATION, HYDROLYTIC STABILITY MET-TECH SYSTEMS LIMITED (CA) 1996-01-30 US claimed
US-5328626-A Extraction of metals from aqueous solutions MET-TECH SYSTEMS, LTD. (CA) 1994-07-12 US claimed
EP-0598747-A1 N-ETHYL HYDROXAMIC ACID CHELANTS. MONSANTO CO (US) 1994-06-01 EP claimed
WO-1993002047-A1 N-ETHYL HYDROXAMIC ACID CHELANTS MONSANTO COMPANY (US) 1993-02-04 WO claimed
EP-0598747-B1 N-ETHYL HYDROXAMIC ACID CHELANTS MET TECH SYSTEMS LTD (CA) 1996-04-24 EP disclosed
US-5487842-A LOW VISCOSITY, RAPID PHASE SEPARATION, HYDROLYTIC STABILITY MET-TECH SYSTEMS LIMITED (CA) 1996-01-30 US disclosed
US-5328626-A Extraction of metals from aqueous solutions MET-TECH SYSTEMS, LTD. (CA) 1994-07-12 US disclosed
EP-0598747-A1 N-ETHYL HYDROXAMIC ACID CHELANTS. MONSANTO CO (US) 1994-06-01 EP disclosed
EP-0283740-B1 Oxidative dissolution of gallium arsenide and separation of gallium from arsenic MONSANTO CO (US) 1993-11-24 EP disclosed
WO-1993002047-A1 N-ETHYL HYDROXAMIC ACID CHELANTS MONSANTO COMPANY (US) 1993-02-04 WO disclosed
US-5174917-A Compositions containing n-ethyl hydroxamic acid chelants MONSANTO COMPANY (US) 1992-12-29 US disclosed
US-5030427-A Washing solutions of n-organohydaoxamic acid complexes MONSANTO COMPANY (US) 1991-07-09 US disclosed
US-4943646-A WITH N-ORGANOHYDROXAMIC ACID MONSANTO COMPANY (US) 1990-07-24 US disclosed
US-4939299-A Succinyl dihydroxamic acids MONSANTO COMPANY (US) 1990-07-03 US disclosed
EP-0344143-A2 Gallium purification MONSANTO COMPANY (US) 1989-11-29 EP disclosed
EP-0283740-A2 Oxidative dissolution of gallium arsenide and separation of gallium from arsenic MONSANTO COMPANY (US) 1988-09-28 EP disclosed
US-4759917-A Contacting with oxidizing agent and hydroxamic acid to convert gallium to gallium-hydroxamic acid complex, and oxidize arsanic MONSANTO COMPANY (US) 1988-07-26 US disclosed
US-4741887-A Gallium complexes and solvent extraction of gallium MONSANTO COMPANY (US) 1988-05-03 US disclosed