Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991323 | 0.86 | MAPT (0.51) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL9434473 | 0.83 | PKMYT1 (0.56) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL8977928 | 0.80 | VCP (0.63) | MAPTKMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL7980595 | 0.75 | MAPT (0.62) | MAPTKMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL2478090 | 0.73 | PRKDC (0.58) | MAPTKMT2AMEN1MAPK1VCP | |
| SCHEMBL10988362 | 0.72 | KDM4E (0.48) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL7169368 | 0.72 | CYP3A4 (0.52) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL12285459 | 0.72 | MAPT (0.52) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27660780 | 0.71 | MAPT (0.51) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL27617962 | 0.70 | GAA (0.60) | MAPTKMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525480-A | USED FOR DETERMINATION OF HYDROLASES; COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0433855-A2 | N- and O-substituted aminophenol derivatives, intermediates for their preparation, their use as hydrolase substrates, a corresponding assay and diagnostic agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |