Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009117 | 0.81 | GAA (0.46) | NPC1TNIKALDH1A1MAPTHTT | |
| SCHEMBL8977902 | 0.81 | NPC1 (0.44) | AMY1ANPC1KDM1AALDH1A1MAPT | |
| SCHEMBL11686412 | 0.78 | MAPT (0.46) | AMY1ANPC1TNIKKDM1AALDH1A1 | |
| SCHEMBL7003540 | 0.78 | ALDH1A1 (0.65) | NPC1TNIKALDH1A1MAPTHTT | |
| SCHEMBL3893822 | 0.77 | APP (0.57) | AMY1ANPC1KDM1AALDH1A1MAPT | |
| SCHEMBL11414246 | 0.76 | MEN1 (0.49) | AMY1ANPC1TNIKKDM1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11738417 | 0.75 | APP (0.55) | AMY1ANPC1KDM1AALDH1A1MAPT | |
| SCHEMBL11849550 | 0.74 | MAPT (0.52) | AMY1ANPC1KDM1AALDH1A1MAPT | |
| SCHEMBL11509537 | 0.74 | TDP1 (0.42) | TNIKALDH1A1MAPTHTTTDP1 | |
| SCHEMBL11217909 | 0.74 | GAA (0.54) | NPC1TNIKALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525480-A | USED FOR DETERMINATION OF HYDROLASES; COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0433855-A2 | N- and O-substituted aminophenol derivatives, intermediates for their preparation, their use as hydrolase substrates, a corresponding assay and diagnostic agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |