Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977973 | 0.81 | AMY1A (0.45) | NPC1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8977999 | 0.80 | NPC1 (0.46) | NPC1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9479616 | 0.70 | ALDH1A1 (0.65) | NPC1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL222247 | 0.70 | ALDH1A1 (0.65) | NPC1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL24459914 | 0.69 | GAA (0.47) | NPC1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL3893822 | 0.69 | APP (0.57) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL11441737 | 0.69 | ALDH1A1 (0.50) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3212678 | 0.69 | HSD17B10 (0.50) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11330823 | 0.69 | ALDH1A1 (0.41) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL11738417 | 0.67 | APP (0.55) | NPC1MAPTSMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525480-A | USED FOR DETERMINATION OF HYDROLASES; COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0433855-A2 | N- and O-substituted aminophenol derivatives, intermediates for their preparation, their use as hydrolase substrates, a corresponding assay and diagnostic agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |