SCHEMBL8978033

SCHEMBL8978033

CC(=O)Nc1c(I)c(CN)c(I)c(C(=O)NC(CO)CO)c1I

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.58
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8978151 0.89 LMNA (0.71) LMNASMN1; SMN2
SCHEMBL10875551 0.85 LMNA (0.63) LMNASMN1; SMN2
SCHEMBL8373498 0.85 LMNA (0.66) LMNASMN1; SMN2
SCHEMBL619948 0.80 LMNA (0.60) LMNASMN1; SMN2
SCHEMBL9189587 0.78 LMNA (0.61) LMNASMN1; SMN2
SCHEMBL11379598 0.78 LMNA (0.72) LMNASMN1; SMN2
SCHEMBL10885205 0.77 LMNA (0.53) LMNASMN1; SMN2
SCHEMBL7591769 0.77 LMNA (0.56) LMNA
SCHEMBL17264622 0.76 LMNA (0.83) LMNASMN1; SMN2
SCHEMBL7592512 0.75 LMNA (0.64) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707572-A1 IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME BRACCO S.p.A. (IT) 1996-04-24 EP disclosed
WO-1995001966-A1 IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME BRACCO S.P.A. (IT) 1995-01-19 WO disclosed