Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379598 | 0.86 | LMNA (0.72) | LMNASMN1; SMN2HSD17B10HPGDPTPRB | |
| SCHEMBL10875389 | 0.84 | LMNA (0.68) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL28215227 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL9564018 | 0.79 | LMNA (0.63) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL8978033 | 0.77 | LMNA (0.58) | LMNASMN1; SMN2 | |
| SCHEMBL9000039 | 0.75 | LMNA (0.58) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL22680970 | 0.74 | LMNA (0.68) | LMNASMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL10877148 | 0.74 | LMNA (0.52) | LMNASMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Diatrizoic Acid SCHEMBL7615048 | 0.72 | LMNA (0.67) | LMNASMN1; SMN2HSD17B10HPGDPTPRB | |
| SCHEMBL8374104 | 0.72 | LMNA (0.55) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607123-A | X-RAY CONTRAST AGENTS | DR. FRANZ KOHLER CHEMIE GMBH (DE) | 1986-08-19 | — | — | US | disclosed |