Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20540759 | 1.00 | POLB (0.44) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL20540937 | 1.00 | POLB (0.44) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL20540935 | 1.00 | POLB (0.44) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL20540761 | 1.00 | POLB (0.44) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL14016358 | 0.84 | CYP2C19 (0.45) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL16892281 | 0.81 | POLB (0.39) | POLBTDP1CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL16892207 | 0.81 | APLNR (0.37) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL16892208 | 0.81 | APLNR (0.37) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL8978055 | 0.78 | POLB (0.57) | POLBTDP1CYP2C19GABRR1CYP2D6 | |
| SCHEMBL23366184 | 0.77 | CYP2C19 (0.50) | CYP2C19GABRR1CYP2D6CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-06 | — | — | US | disclosed |
| US-20180305368-A1 | ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS | U.S. DEPARTMENT OF ENERGY | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305368-A1 | ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS | PPIH, HMBS, PPOX | POLB 779/4885TDP1 3733/4885CYP2C19 148/4885 |
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | PPIH, HMBS, PPOX | POLB 779/4885TDP1 3733/4885CYP2C19 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.