SCHEMBL8978084

SCHEMBL8978084

C[N+](C)(C)CCc1ccc(N=C=S)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 2/20 0.68
ALDH1A1 P00352 1/20 0.48
PKM P14618 1/20 0.48
MIF P14174 5/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CHRM2 P08172 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP3A4 P08684 2/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALOX12 P18054 1/20 0.34
TSHR P16473 1/20 0.34
OPRD1 P41143 1/20 0.33
TRPA1 O75762 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8978144 0.98 P2RY6 (0.66) P2RY6ALDH1A1PKMMIFCA1
SCHEMBL1853024 0.82 P2RY6 (1.00) P2RY6MIFCA1CA2CHRM1
SCHEMBL9547715 0.82 P2RY6 (1.00) P2RY6MIFCA1CA2CHRM1
SCHEMBL5186242 0.79 P2RY6 (0.76) P2RY6MIFCA1CA2HSD17B10
SCHEMBL347652 0.76 P2RY6 (0.79) P2RY6MIFCA1CA2CHRM1
SCHEMBL1457664 0.76 P2RY6 (0.70) P2RY6ALDH1A1MIFCA1CA2
SCHEMBL8503279 0.75 P2RY6 (0.76) P2RY6ALDH1A1MIFCA1CA2
SCHEMBL6417472 0.75 P2RY6 (0.76) P2RY6MIFCA1CA2CHRM1
SCHEMBL3880561 0.75 P2RY6 (0.76) P2RY6ALDH1A1MIFCA1CA2
SCHEMBL27467439 0.75 P2RY6 (0.76) P2RY6MIFCA1CA2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5534440-A ISOTHIOCYANATE, IONIZABLE GROUP BIOMEDICAL RESEARCH CENTRE LIMITED (CA) 1996-07-09 US claimed
EP-0573482-B1 COMPOUNDS AND METHODS FOR SEQUENCING AMINO ACIDS B R CENTRE LIMITED (CA) 1995-12-27 EP claimed
WO-1992014702-A1 COMPOUNDS AND METHODS FOR SEQUENCING AMINO ACIDS B.R. CENTRE LIMITED (CA) 1992-09-03 WO claimed
US-5534440-A ISOTHIOCYANATE, IONIZABLE GROUP BIOMEDICAL RESEARCH CENTRE LIMITED (CA) 1996-07-09 US disclosed
US-5534440-A ISOTHIOCYANATE, IONIZABLE GROUP BIOMEDICAL RESEARCH CENTRE LIMITED (CA) 1996-07-09 US disclosed
EP-0573482-B1 COMPOUNDS AND METHODS FOR SEQUENCING AMINO ACIDS B R CENTRE LIMITED (CA) 1995-12-27 EP disclosed
US-5240859-A Coupling terminal amino acid with thioisocyanate, cleaving and identification; spectometrometric analysis B.R. CENTRE LIMITED (CA) 1993-08-31 US disclosed
US-5240859-A Coupling terminal amino acid with thioisocyanate, cleaving and identification; spectometrometric analysis B.R. CENTRE LIMITED (CA) 1993-08-31 US disclosed
WO-1992014702-A1 COMPOUNDS AND METHODS FOR SEQUENCING AMINO ACIDS B.R. CENTRE LIMITED (CA) 1992-09-03 WO disclosed
WO-1992014702-A1 COMPOUNDS AND METHODS FOR SEQUENCING AMINO ACIDS B.R. CENTRE LIMITED (CA) 1992-09-03 WO disclosed