Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359643 | 0.91 | LMNA (0.55) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2011397 | 0.84 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL16875799 | 0.84 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL622562 | 0.83 | LMNA (0.48) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3426791 | 0.83 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL21211562 | 0.82 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL30980833 | 0.82 | LMNA (0.47) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7047230 | 0.81 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL14790185 | 0.79 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL11005886 | 0.78 | CYP2C19 (0.52) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101970381-B | Process for iodination of aromatic compounds | BRACCO IMAGING SPA | 2013-10-23 | — | — | CN | disclosed |
| EP-0707572-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.p.A. (IT) | 1996-04-24 | — | — | EP | disclosed |