Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990865 | 0.76 | GAA (0.66) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4900724 | 0.76 | GAA (0.70) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7353744 | 0.76 | GAA (0.75) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL15573824 | 0.75 | GAA (0.64) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL27703735 | 0.74 | MEN1 (0.83) | GAAMEN1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1128739 | 0.74 | GAA (0.72) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8978253 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TSHRCYP2C19 | |
| SCHEMBL2942358 | 0.73 | MEN1 (0.96) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL2109312 | 0.72 | GAA (0.63) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL93948 | 0.72 | GAA (0.75) | GAAMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378930-B1 | Cyclic urea derivative | NIPPON PAINT CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5385985-A | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |