Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978324 | 0.97 | ALKBH5 (0.42) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978232 | 0.95 | ALKBH5 (0.39) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978334 | 0.94 | NPSR1 (0.40) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978350 | 0.94 | TRPV1 (0.38) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978352 | 0.94 | ALKBH5 (0.38) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978390 | 0.94 | ALKBH5 (0.38) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978368 | 0.92 | ALDH1A1 (0.41) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978300 | 0.92 | PDGFRB (0.40) | PDGFRBFGFR1KDRTRPV1ALDH1A1 | |
| SCHEMBL8978237 | 0.92 | TRPV1 (0.40) | ALKBH5PDGFRBFGFR1KDRTRPV1 | |
| SCHEMBL8978362 | 0.91 | PDGFRB (0.38) | ALKBH5PDGFRBFGFR1KDRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484940-A | ULTRAVIOLET RADIATION ABSORBERS FOR PLASTICS, AMYLOID PEPTIDE INHIBITORS, ALZHEIMER*S DISEASE | ATHENA NEUROSCIENCES, INC. | 1996-01-16 | — | — | US | disclosed |