Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978279 | 0.90 | PTGS2 (0.69) | PTGS2ABCB1PTGS1CNR2AKR1C3 | |
| SCHEMBL8978347 | 0.80 | PTGS2 (0.70) | PTGS2ABCB1PTGS1CNR2AKR1C3 | |
| SCHEMBL19749125 | 0.78 | PTGS2 (0.89) | PTGS2PTGS1CNR2AKR1C3 | |
| SCHEMBL2237296 | 0.77 | ABCB1 (1.00) | PTGS2ABCB1PTGS1AKR1C3 | |
| SCHEMBL17378105 | 0.77 | PTGS2 (0.81) | PTGS2PTGS1CNR2AKR1C3 | |
| SCHEMBL8978411 | 0.77 | PTGS2 (0.74) | PTGS2CNR2AKR1C3 | |
| SCHEMBL26771824 | 0.77 | PTGS2 (0.77) | PTGS2ABCB1PTGS1CNR2AKR1C3 | |
| SCHEMBL8978246 | 0.76 | PTGS2 (0.85) | PTGS2ABCB1PTGS1CNR2AKR1C3 | |
| SCHEMBL2237214 | 0.76 | PTGS2 (0.80) | PTGS2ABCB1PTGS1CNR2AKR1C3 | |
| SCHEMBL8978218 | 0.76 | AKR1C3 (0.53) | PTGS2ABCB1PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484940-A | ULTRAVIOLET RADIATION ABSORBERS FOR PLASTICS, AMYLOID PEPTIDE INHIBITORS, ALZHEIMER*S DISEASE | ATHENA NEUROSCIENCES, INC. | 1996-01-16 | — | — | US | disclosed |