Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978267 | 0.92 | PTGS2 (0.70) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL8978246 | 0.83 | PTGS2 (0.85) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL2007480 | 0.82 | AKR1C3 (0.80) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL8978311 | 0.80 | PTGS2 (0.86) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL8978281 | 0.80 | PTGS2 (0.65) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL8978206 | 0.79 | PTGS2 (0.75) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL29113899 | 0.79 | PTGS2 (0.85) | PTGS2AKR1C3CNR2 | |
| SCHEMBL8879886 | 0.79 | PTGS2 (0.87) | PTGS2AKR1C3CNR2 | |
| SCHEMBL13813542 | 0.78 | PTGS2 (1.00) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL20349623 | 0.78 | PTGS2 (0.79) | PTGS2AKR1C3CNR2AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484940-A | ULTRAVIOLET RADIATION ABSORBERS FOR PLASTICS, AMYLOID PEPTIDE INHIBITORS, ALZHEIMER*S DISEASE | ATHENA NEUROSCIENCES, INC. | 1996-01-16 | — | — | US | disclosed |