Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | DPYD | Q12882 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445914 | 0.71 | CYP1A2 (0.44) | ALDH1A1LMNAMAPK1HPGDMAPT | |
| SCHEMBL8978389 | 0.67 | CRBN (0.50) | RAB9ANPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL8978384 | 0.67 | CRBN (0.50) | RAB9ANPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL27701056 | 0.66 | BRD4 (0.33) | KDM4E | |
| SCHEMBL2181559 | 0.66 | — | — | |
| Benzaldehyde SCHEMBL27944564 | 0.65 | CYP2A6 (0.47) | ALDH1A1LMNAMAPK1TRPA1ALOX5 | |
| SCHEMBL9277794 | 0.64 | — | — | |
| SCHEMBL45000 | 0.61 | GSK3A (0.54) | RAB9ANPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL991992 | 0.61 | NPC1 (0.52) | RAB9ANPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL2561874 | 0.60 | CYP2A6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705265-A1 | NOVEL CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITION ACTIVITY | Euroceltique S.A. (LU) | 1996-04-10 | — | — | EP | disclosed |