Sugi Predict

Sugi Predict / Compounds / SCHEMBL45000

SCHEMBL45000

SCHEMBL45000

O=c1cc[nH]c(=O)n1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3A P49840 3/20 0.54
▸ GSK3B P49841 3/20 0.54
▸ GAA P10253 1/20 0.54
▸ ALDH1A1 P00352 3/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MAPK1 P28482 1/20 0.42
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ NTRK1 P04629 1/20 0.40
▸ IGF1R P08069 1/20 0.40
▸ FGFR1 P11362 1/20 0.40
▸ NTRK3 Q16288 1/20 0.40
▸ NTRK2 Q16620 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ JAK2 O60674 1/20 0.39
▸ JAK3 P52333 1/20 0.39
▸ DDB1 Q16531 1/20 0.38
▸ CRBN Q96SW2 1/20 0.38
▸ HSD17B10 Q99714 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL27809446 0.91 GSK3A (0.46) GSK3AGSK3BGAAALDH1A1LMNA
SCHEMBL712191 0.80 ALDH1A1 (0.49) GSK3AGSK3BGAAALDH1A1LMNA
SCHEMBL5325747 0.80 F2 (0.47) GSK3AGSK3BALDH1A1LMNAMAPK1
SCHEMBL30227813 0.80 MAPT (0.41) GSK3AGSK3BALDH1A1LMNAMEN1
SCHEMBL22679805 0.78 JAK2 (0.43) GSK3AGSK3BGAAALDH1A1LMNA
SCHEMBL7133475 0.78 FAAH (0.46) GSK3AGSK3BGAAALDH1A1LMNA
SCHEMBL7037359 0.76 ELANE (0.38) ALDH1A1MAPK1NPC1JAK2JAK3
SCHEMBL5289089 0.76 NPC1 (0.38) GSK3BGAAALDH1A1MAPK1NPC1
SCHEMBL7522262 0.75 PARP1 (0.48) GAAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL4715222 0.73 JAK2 (0.44) GSK3AGSK3BGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243149-A1 IMPROVED PROCESS FOR RECOVERING N,N-DIMETHYLFORMAMIDE (DMF) FROM AN AQUEOUS PROCESS STREAM BASF Agro B.V. (NL) 2025-07-31 — — US claimed
CN-119032085-A Improved process for recovery of N, N-Dimethylformamide (DMF) from aqueous process streams 巴斯夫农业公司 2024-11-26 — — CN claimed
CN-117751102-A Herbicidal phenyluracils 巴斯夫欧洲公司 2024-03-22 — — CN claimed
WO-2023198484-A1 IMPROVED PROCESS FOR RECOVERING N,N-DIMETHYLFORMAMIDE (DMF) FROM AN AQUEOUS PROCESS STREAM BASF Agro B.V. (NL) 2023-10-19 — — WO claimed
CN-109232442-B Aryl uracil compound or agriculturally and pharmaceutically acceptable salt thereof, preparation method thereof and herbicide composition 深圳大学 2021-11-02 — — CN claimed
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines BASF SE (DE) 2019-07-02 — — US claimed
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2017-12-28 — — US claimed
US-20160106849-A1 FORMULATIONS OF PHENYL URACIL COMPOUNDS ABBVIE INC. 2016-04-21 — — US claimed
US-20160037777-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2016-02-11 — — US claimed
US-8288318-B2 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides DOW AGROSCIENCES, LLC. (US) 2012-10-16 — — US claimed
US-6617282-B2 Useful as herbicides, defoliants and desiccants. ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-09-09 — — US claimed
US-20030096990-A1 Processes for preparing 3-phenyl-2,4(1H, 3H)-pyrimidinediones ISHIHARA SANGYO KAISHA, LTD. 2003-05-22 — — US claimed
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 — — US claimed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 — — US claimed
CN-1253550-A Phenyl-uracil derivatives with herbicidal action BAYER AG (DE) 2000-05-17 — — CN claimed
EP-0716653-B1 SUBSTITUTED 1-AMINO-3-PHENYLURACILS WITH HERBICIDAL ACTIVITIES BASF AG (DE) 2000-04-26 — — EP claimed
EP-0716653-A1 SUBSTITUTED 1-AMINO-3-PHENYLURACILS WITH HERBICIDAL ACTIVITIES BASF AKTIENGESELLSCHAFT (DE) 1996-06-19 — — EP claimed
WO-1995006641-A1 SUBSTITUTED 1-AMINO-3-PHENYLURACILS WITH HERBICIDAL ACTIVITIES BASF AKTIENGESELLSCHAFT (DE) 1995-03-09 — — WO claimed
EP-0604491-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF Aktiengesellschaft (DE) 1994-07-06 — — EP claimed
WO-1993006090-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-04-01 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 GSK3A 1548/4885GSK3B 1153/4885GAA 2044/4885
US-20160106849-A1 FORMULATIONS OF PHENYL URACIL COMPOUNDS UNG, UMPS, TYMP GSK3A 3816/4885GSK3B 3875/4885GAA 263/4885
US-20160037777-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 GSK3A 1548/4885GSK3B 1153/4885GAA 2044/4885
US-20030096990-A1 Processes for preparing 3-phenyl-2,4(1H, 3H)-pyrimidinediones HPD, DDT, DPYD GSK3A 3712/4885GSK3B 3618/4885GAA 456/4885
US-20250243149-A1 IMPROVED PROCESS FOR RECOVERING N,N-DIMETHYLFORMAMIDE (DMF) FROM AN AQUEOUS PROCESS STREAM NAAA, NIT2, FH GSK3A 3722/4885GSK3B 4180/4885GAA 2739/4885
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 GSK3A 4562/4885GSK3B 4537/4885GAA 3824/4885
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 GSK3A 1548/4885GSK3B 1153/4885GAA 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.