Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | DUT | P33316 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPYD | Q12882 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978389 | 1.00 | CRBN (0.50) | CRBNDDB1NPC1HPGDALDH1A1 | |
| SCHEMBL5907658 | 0.73 | CRBN (0.52) | CRBNDDB1DUTCYP1A2 | |
| SCHEMBL2181554 | 0.67 | CRBN (0.54) | CRBNDDB1ALDH1A1L3MBTL1DUT | |
| SCHEMBL3541014 | 0.67 | CRBN (0.54) | CRBNDDB1ALDH1A1DUTLMNA | |
| SCHEMBL9019445 | 0.67 | CRBN (0.44) | CRBNDDB1ALDH1A1DUTKMT2A | |
| SCHEMBL30991351 | 0.67 | SMN1; SMN2 (0.47) | CRBNDDB1DUTKMT2AKDM4E | |
| SCHEMBL11268394 | 0.66 | CRBN (0.47) | CRBNDDB1NPC1ALDH1A1RAB9A | |
| SCHEMBL11268402 | 0.66 | CRBN (0.47) | CRBNDDB1NPC1ALDH1A1RAB9A | |
| SCHEMBL9277788 | 0.65 | CRBN (0.45) | CRBNDDB1ALDH1A1L3MBTL1DUT | |
| SCHEMBL3752207 | 0.63 | CRBN (0.40) | CRBNDDB1ALDH1A1DUTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705265-A1 | NOVEL CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITION ACTIVITY | Euroceltique S.A. (LU) | 1996-04-10 | — | — | EP | disclosed |