Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.63 |
| ▸ | CNR2 | P34972 | 3/20 | 0.61 |
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978267 | 0.87 | PTGS2 (0.70) | PTGS2AKR1C3CNR2CNR1AKR1C2 | |
| SCHEMBL8978246 | 0.87 | PTGS2 (0.85) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL8978206 | 0.83 | PTGS2 (0.75) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL8978411 | 0.80 | PTGS2 (0.74) | PTGS2AKR1C3CNR2AKR1C2 | |
| SCHEMBL8978311 | 0.80 | PTGS2 (0.86) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL20349624 | 0.79 | PTGS2 (0.83) | PTGS2AKR1C3CNR2AKR1C2HIF1A | |
| SCHEMBL4549122 | 0.79 | PTGS2 (1.00) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL8978347 | 0.77 | PTGS2 (0.70) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL20349623 | 0.77 | PTGS2 (0.79) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL8978290 | 0.77 | PLA2G2A (0.74) | PTGS2LMNACYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484940-A | ULTRAVIOLET RADIATION ABSORBERS FOR PLASTICS, AMYLOID PEPTIDE INHIBITORS, ALZHEIMER*S DISEASE | ATHENA NEUROSCIENCES, INC. | 1996-01-16 | — | — | US | disclosed |