SCHEMBL897856

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10246834	0.88	L3MBTL1 (0.42)	L3MBTL1ALDH1A1MAPTMAPK1KMT2A
	SCHEMBL602723	0.87	CA12 (0.52)	AKR1C3AKR1C2L3MBTL1ALDH1A1MAPK1
	SCHEMBL897637	0.85	ALDH1A1 (0.41)	L3MBTL1ALDH1A1MAPTMAPK1KMT2A
	SCHEMBL897822	0.82	CNR2 (0.54)	L3MBTL1ALDH1A1MAPTMAPK1KMT2A
	SCHEMBL3753644	0.79	AKR1C3 (0.49)	AKR1C3AKR1C2L3MBTL1MAPK1RAB9A
	SCHEMBL897701	0.78	ALDH1A1 (0.50)	L3MBTL1ALDH1A1MAPTMAPK1KMT2A
	SCHEMBL27181142	0.78	HTT (0.54)	AKR1C3AKR1C2ALDH1A1MAPTKMT2A
	SCHEMBL27974199	0.78	AKR1C3 (0.48)	AKR1C3AKR1C2ALDH1A1MAPTSMN1; SMN2
	SCHEMBL22473335	0.77	ATM (0.49)	AKR1C3AKR1C2L3MBTL1KMT2AMEN1
	SCHEMBL2006312	0.76	AKR1C3 (0.47)	AKR1C3AKR1C2ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.