Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072642 | 0.82 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL8978517 | 0.79 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL5429664 | 0.79 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL12490798 | 0.77 | APOBEC3G (0.50) | ALDH1A1MEN1KMT2AKDM4EGFER | |
| SCHEMBL17673661 | 0.77 | APOBEC3G (0.68) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL13729062 | 0.77 | TDP1 (0.75) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL8978622 | 0.76 | HPGD (0.79) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL9402205 | 0.75 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL8978542 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL8978623 | 0.74 | APOBEC3G (1.00) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |