SCHEMBL8978602

SCHEMBL8978602

O=S(=O)(c1ccc(Br)cc1)c1ccc2cc(S(=O)(=O)c3ccc(Br)cc3)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.48
PLCG1 P19174 1/20 0.46
HTR6 P50406 3/20 0.46
CA12 O43570 2/20 0.43
MMP2 P08253 2/20 0.43
CA9 Q16790 1/20 0.43
CA1 P00915 1/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 3/20 0.43
CA14 Q9ULX7 1/20 0.42
AKR1B1 P15121 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PKM P14618 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526773 0.91 CYP2A6 (0.50) CA2PLCG1HTR6CA12MMP2
SCHEMBL22758444 0.86 ALDH1A1 (0.39) CA2PLCG1HTR6CA12MMP2
SCHEMBL2122562 0.85 CA2 (0.62) CA2PLCG1HTR6CA12MMP2
SCHEMBL8978700 0.85 CA2 (0.62) CA2PLCG1HTR6CA12MMP2
SCHEMBL250285 0.85 CA2 (0.62) CA2PLCG1HTR6CA12MMP2
SCHEMBL18187419 0.85 CA2 (0.62) CA2PLCG1HTR6CA12MMP2
SCHEMBL5632873 0.85 GAA (0.49) CA2CA12CA9CA1LMNA
SCHEMBL6211177 0.83 CYP2A6 (0.39) CA2HTR6LMNAMAPTHTT
SCHEMBL18187421 0.82 ALDH1A1 (0.58) CA2PLCG1HTR6CA12MMP2
SCHEMBL5632881 0.82 ERN1 (0.41) HTR6LMNAMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US claimed
EP-0411625-B1 Method to produce poly(arylene sulfide/sulfone) polymer PHILLIPS PETROLEUM CO (US) 1996-05-08 EP disclosed
US-5350834-A Thermal stability and purity, zinc compound PHILLIPS PETROLEUM COMPANY (US) 1994-09-27 US disclosed
US-5331069-A Method of treating poly(arylene sulfide sulfone) polymers and polymers PHILLIPS PETROLEUM COMPANY (US) 1994-07-19 US disclosed
US-5298574-A Copolymerizing in presence of n-methyl-2-pyrrolidone, sodium carbonate and sodium hydrogen sulfide PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5298573-A Poly(arylene sulfide sulfone)/poly(arylene sulfide ketone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5286817-A Poly(arylene sulfide)/poly(arylene sulfide sulfone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-02-15 US disclosed
US-5268449-A Containing arylene sulfide and arylene sulfonate segments PHILLIPS PETROLEUM COMPANY (US) 1993-12-07 US disclosed
US-5266674-A Copolymers PHILLIPS PETROLEUM COMPANY (US) 1993-11-30 US disclosed
US-5235034-A Increased melt stability and decreased impurities PHILLIPS PETROLEUM COMPANY (US) 1993-08-10 US disclosed
US-4774276-A ZINC IONS TO IMPROVE MELT STABILITY OF POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1988-09-27 US disclosed
EP-0280325-A2 Melt stabilization of poly (arylene sulfide sulfone) S PHILLIPS PETROLEUM COMPANY (US) 1988-08-31 EP disclosed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP disclosed
US-4301274-A BY REACTING A DIHALOAROMATIC SULFONE, AND AN ALKALI METAL SULFIDE; ENDCAPPING PHILLIPS PETROLEUM COMPANY (US) 1981-11-17 US disclosed
EP-0033906-A1 Process for the production of aromatic sulfide/sulfone polymers PHILLIPS PETROLEUM COMPANY (US) 1981-08-19 EP disclosed
US-4127713-A FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-11-28 US disclosed
US-4102875-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-07-25 US disclosed
US-4070349-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-01-24 US disclosed
US-4016145-A SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE PHILLIPS PETROLEUM COMPANY (US) 1977-04-05 US disclosed