Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EEF2K | O00418 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702588 | 0.75 | GAA (1.00) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL7702586 | 0.75 | GAA (1.00) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL7697041 | 0.72 | PTGS2 (1.00) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL7697044 | 0.72 | PTGS2 (1.00) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL8961998 | 0.71 | PTGS1 (0.56) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL8962112 | 0.71 | PTGS1 (0.56) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL8962003 | 0.71 | PTGS1 (0.56) | GAAPTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL8779582 | 0.70 | CYP1A2 (0.58) | GAAPTGS2PTGS1EEF2KSRC | |
| SCHEMBL8779588 | 0.70 | CYP1A2 (0.58) | GAAPTGS2PTGS1EEF2KSRC | |
| SCHEMBL13045105 | 0.70 | GAA (0.75) | GAAPTGS2PTGS1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494927-A | INHIBITS ACTIVITY OF 5-LIPOXYGENASE AND-OR CYCLOOXYGENASE | WARNER-LAMBERT COMPANY (US) | 1996-02-27 | — | — | US | disclosed |