SCHEMBL8978666

SCHEMBL8978666

CCCCc1cc(F)ccc1S(=O)(=O)c1ccc(F)cc1CCCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
TYR P14679 1/20 0.40
METAP2 P50579 3/20 0.38
MPO P05164 4/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
SLC6A4 P31645 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
GHSR Q92847 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277846 0.87 CA2 (0.44) KDM4EMEN1ALDH1A1LMNAPOLB
SCHEMBL4118278 0.83 KDM4E (0.44) KDM4EKMT2APTGDR2SLC6A4TSHR
SCHEMBL11148043 0.82 MEN1 (0.46) KDM4EMEN1ALDH1A1LMNAPOLB
SCHEMBL9756870 0.79 EDNRB (0.39) MEN1LMNAPOLBGAAHTT
SCHEMBL9333124 0.79 TYR (0.56) KDM4EMEN1ALDH1A1LMNAGAA
SCHEMBL5757189 0.79 PSEN1 (0.39) KDM4EKMT2APTGDR2TSHRMAPK1
SCHEMBL5103997 0.76 TYR (0.46) MEN1HTTKMT2ATYRMPO
SCHEMBL32664555 0.75 KDM4E (0.39) KDM4EMEN1ALDH1A1LMNAPOLB
SCHEMBL19658854 0.74 TYR (0.44) MEN1HTTKMT2ATYRMPO
SCHEMBL3948236 0.74 PSEN1 (0.41) KDM4EKMT2APTGDR2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US claimed
CN-107108895-B Process for the manufacture of poly (aryl ether) s using at least one organic base 索尔维特殊聚合物美国有限责任公司 2020-10-16 CN disclosed
US-10745522-B2 Method for the manufacture of poly(aryl ethers) using at least one organic base SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-08-18 US disclosed
EP-3209708-B1 METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHERS) USING AT LEAST ONE ORGANIC BASE SOLVAY SPECIALTY POLYMERS USA L L C (US) 2019-08-21 EP disclosed
US-20170355821-A1 Method for the manufacture of poly(aryl ethers) using at least one organic base SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-12-14 US disclosed
EP-3209708-A1 METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHERS) USING AT LEAST ONE ORGANIC BASE Solvay Specialty Polymers USA, L.L.C. (US) 2017-08-30 EP disclosed
EP-0411625-B1 Method to produce poly(arylene sulfide/sulfone) polymer PHILLIPS PETROLEUM CO (US) 1996-05-08 EP disclosed
US-5350834-A Thermal stability and purity, zinc compound PHILLIPS PETROLEUM COMPANY (US) 1994-09-27 US disclosed
US-5298574-A Copolymerizing in presence of n-methyl-2-pyrrolidone, sodium carbonate and sodium hydrogen sulfide PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5298573-A Poly(arylene sulfide sulfone)/poly(arylene sulfide ketone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
EP-0280325-A2 Melt stabilization of poly (arylene sulfide sulfone) S PHILLIPS PETROLEUM COMPANY (US) 1988-08-31 EP disclosed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP disclosed
US-4301274-A BY REACTING A DIHALOAROMATIC SULFONE, AND AN ALKALI METAL SULFIDE; ENDCAPPING PHILLIPS PETROLEUM COMPANY (US) 1981-11-17 US disclosed
EP-0033906-A1 Process for the production of aromatic sulfide/sulfone polymers PHILLIPS PETROLEUM COMPANY (US) 1981-08-19 EP disclosed
US-4127713-A FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-11-28 US disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4102875-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-07-25 US disclosed
US-4070349-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-01-24 US disclosed
US-4016145-A SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE PHILLIPS PETROLEUM COMPANY (US) 1977-04-05 US disclosed