SCHEMBL8978668

SCHEMBL8978668

C=CP(C)(=O)OCC(C)C

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383286 0.79 TSHR (0.40) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL11000937 0.76 TSHR (0.47) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL11308545 0.74 TSHR (0.36) TSHR
SCHEMBL20377361 0.74 TSHR (0.36) TSHR
SCHEMBL779857 0.73
SCHEMBL8971191 0.72
SCHEMBL5407738 0.72 NPSR1 (0.39) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL9625572 0.71
SCHEMBL3886857 0.71 TSHR (0.38) TSHRALDH1A1CYP3A4GAANPSR1
SCHEMBL11312668 0.71 TSHR (0.38) TSHRALDH1A1CYP3A4GAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200270288-A1 ORGANOPHOSPHORUS COMPOUND AND FLAME RETARDANT AGENT COMPRISING SAME, AND METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND MARUZEN PETROCHEMICAL CO., LTD. (JP) 2020-08-27 US disclosed
US-10479809-B2 Method for producing alkenyl phosphorus compound MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-11-19 US disclosed
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-08-29 US disclosed
EP-3401321-A1 ORGANOPHOSPHORUS COMPOUND AND FLAME RETARDANT AGENT COMPRISING SAME, AND METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND Maruzen Petrochemical Co., Ltd. (JP) 2018-11-14 EP disclosed
EP-0329595-B1 Process for preparing alkyl esters of alkenylphosphinic acid HOECHST AG (DE) 1996-05-08 EP disclosed
US-4960919-A Process for the preparation of alkyl alkenylphosphinates HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0329595-A2 Process for preparing alkyl esters of alkenylphosphinic acid HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479809-B2 Method for producing alkenyl phosphorus compound ORC3, OR10J3, ORAI3 TSHR 1438/4885ALDH1A1 1706/4885CYP3A4 53/4885
US-20200270288-A1 ORGANOPHOSPHORUS COMPOUND AND FLAME RETARDANT AGENT COMPRISING SAME, AND METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND ARL1, PFAS, ASH2L TSHR 447/4885ALDH1A1 2921/4885CYP3A4 692/4885
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND ORC3, OR10J3, ALK TSHR 1162/4885ALDH1A1 1631/4885CYP3A4 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.