Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102247 | 0.89 | KLKB1 (0.37) | SMN1; SMN2TDP1NR4A2MAPTATM | |
| SCHEMBL13464551 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2TDP1NR4A2MAPTATM | |
| SCHEMBL10106951 | 0.88 | ATM (0.39) | SMN1; SMN2TDP1MAPTEGFRATM | |
| SCHEMBL6651346 | 0.87 | L3MBTL1 (0.36) | SMN1; SMN2HSD17B10TDP1MAPTL3MBTL1 | |
| SCHEMBL10102251 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2TDP1NR4A2MAPTATM | |
| SCHEMBL29913570 | 0.86 | KDM4E (0.36) | SMN1; SMN2TDP1NR4A2MAPTATM | |
| SCHEMBL8978570 | 0.86 | KDM4E (0.36) | SMN1; SMN2TDP1NR4A2MAPTATM | |
| SCHEMBL8978531 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2HSD17B10TDP1NR4A2MAPT | |
| SCHEMBL5645426 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2TDP1NR4A2MAPTEGFR | |
| SCHEMBL10102253 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1MAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | claimed |
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | claimed |
| US-5573712-A | PHOTOCHROMIC ARTICLE COMPRISING ORGANIC HOST AND THE PHOTOCHROMIC NAPHTHOPYRAN | TRANSITIONS OPTICAL, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |