Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978679 | 0.87 | SMN1; SMN2 (0.34) | L3MBTL1TDP1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL6653402 | 0.81 | L3MBTL1 (0.39) | L3MBTL1ADORA2BTDP1ALDH1A1TP53 | |
| SCHEMBL6651568 | 0.81 | HTT (0.33) | KDM4ETP53HSD17B10TSHRMAPT | |
| SCHEMBL6650625 | 0.80 | MEN1 (0.35) | L3MBTL1ALDH1A1KDM4ENPSR1HSD17B10 | |
| SCHEMBL6653783 | 0.79 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KDM4ETP53HSD17B10 | |
| SCHEMBL10102247 | 0.78 | KLKB1 (0.37) | L3MBTL1TDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10106951 | 0.76 | ATM (0.39) | L3MBTL1TDP1ALDH1A1NPSR1TP53 | |
| SCHEMBL13464551 | 0.76 | SMN1; SMN2 (0.38) | L3MBTL1TDP1ALDH1A1KDM4ETP53 | |
| SCHEMBL10102251 | 0.75 | SMN1; SMN2 (0.37) | L3MBTL1TDP1ALDH1A1KDM4ETP53 | |
| SCHEMBL17929237 | 0.75 | TSHR (0.36) | L3MBTL1ADORA2BTDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | claimed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | claimed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | claimed |
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | disclosed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007078-A1 | Novel substituted naphthopyrans | CRYZ, NR2E3, UACA | L3MBTL1 4785/4885ADORA2B 4289/4885TDP1 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.