Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018723 | 0.92 | GRM5 (0.44) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL8978883 | 0.91 | CYP2A6 (0.55) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL12700668 | 0.90 | GRM5 (0.40) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL8979153 | 0.88 | FFAR1 (0.41) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL8979137 | 0.88 | FFAR1 (0.41) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL9293057 | 0.86 | ALDH1A1 (0.48) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL14884228 | 0.86 | FFAR1 (0.35) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL91864 | 0.86 | GRM5 (0.40) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL8978909 | 0.85 | FFAR1 (0.45) | GRM5KCNH2CYP2A6FFAR1 | |
| SCHEMBL8978868 | 0.85 | FFAR1 (0.45) | GRM5KCNH2CYP2A6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5356558-A | Compatibility, high speed response | SEIKO EPSON CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |