Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018723 | 0.94 | GRM5 (0.44) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL19403026 | 0.91 | GRM5 (0.37) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL15077190 | 0.91 | GRM5 (0.39) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL8979109 | 0.86 | GRM5 (0.44) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL23602326 | 0.86 | ALDH1A1 (0.47) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL15014376 | 0.86 | CYP1A2 (0.46) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL20005194 | 0.85 | GRM5 (0.40) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL13198905 | 0.85 | APP (0.46) | GRM5KCNH2ATML3MBTL1 | |
| SCHEMBL13198903 | 0.85 | APP (0.39) | GRM5KCNH2CYP1A2MEN1KMT2A | |
| SCHEMBL23600265 | 0.85 | FFAR1 (0.36) | GRM5KCNH2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| WO-2023232753-A1 | FERROELECTRIC SMECTIC LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-12-07 | — | — | WO | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| EP-3810724-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-22 | — | — | EP | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-20230313043-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11762241-B2 | Device for the regulation of light transmission | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-20080167482-A1 | mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | MERCK PATENT GMBH (DE) | 2008-05-22 | — | — | US | disclosed |
| US-20080100776-A1 | Liquid Crystal Display Device and Electronic Device Having the Same | SHARP KABUSHIKI KAISHA (JP) | 2008-05-01 | — | — | US | disclosed |
| US-7294368-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-11-13 | — | — | US | disclosed |
| US-20070229732-A1 | CHIRAL COMPOUNDS | TAUGERBECK ANDREAS | 2007-10-04 | — | — | US | disclosed |
| US-7258903-B2 | Fast switching liquid crystal compositions for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-08-21 | — | — | US | disclosed |
| US-7255811-B2 | Tolane derivatives and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7223450-B2 | Chiral compounds | MERCK GMBH (DE) | 2007-05-29 | — | — | US | disclosed |
| US-7220464-B2 | Nematic liquid-crystal mixture, and displays containing same | MERCK PATENT GESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-7198828-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT (DE) | 2007-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | GRM5 3081/4885KCNH2 117/4885CA12 1797/4885 |
| US-20070229732-A1 | CHIRAL COMPOUNDS | F12, F2, C1S | GRM5 4198/4885KCNH2 2573/4885CA12 822/4885 |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | CRY1, CRY2, IK | GRM5 2951/4885KCNH2 1169/4885CA12 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.