SCHEMBL8979259

SCHEMBL8979259

CC(C)(C)C(I)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
ADRA1A P35348 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
PGD P52209 1/20 0.35
TSHR P16473 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
MAPT P10636 2/20 0.34
GABRR1 P24046 2/20 0.33
LMNA P02545 1/20 0.33
CACNA2D1 P54289 2/20 0.32
CACNB3 P54284 1/20 0.32
CACNA1C Q13936 1/20 0.32
PGR P06401 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5196254 0.77 KMT2A (0.30)
SCHEMBL28551189 0.72 SLC22A6 (0.43) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL9117622 0.72 SLC22A6 (0.43) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL667280 0.70 PGD (0.50) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL1572820 0.70 SLC22A6 (0.41) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL23913764 0.70 SLC22A6 (0.41) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL6803525 0.70 PGD (0.50) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL6805671 0.70 PGD (0.50) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL20711453 0.70 SLC22A6 (0.41) SLC22A6TDP1ADRA1ASMN1; SMN2HMGCR
SCHEMBL1551889 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512486-A Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions NORTHEASTERN UNIVERSITY (US) 1996-04-30 US disclosed