Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL112147 | 0.81 | EPHX2 (0.51) | S1PR2S1PR1S1PR3EPHX2ALDH1A1 | |
| Benzene SCHEMBL27649746 | 0.81 | EPHX2 (0.51) | S1PR2S1PR1S1PR3EPHX2ALDH1A1 | |
| Benzene SCHEMBL28758814 | 0.81 | EPHX2 (0.51) | S1PR2S1PR1S1PR3EPHX2ALDH1A1 | |
| Benzene SCHEMBL11150225 | 0.81 | EPHX2 (0.51) | S1PR2S1PR1S1PR3EPHX2ALDH1A1 | |
| Benzene SCHEMBL27649739 | 0.81 | EPHX2 (0.51) | S1PR2S1PR1S1PR3EPHX2ALDH1A1 | |
| Pyrene SCHEMBL28128984 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAMAPK1KMT2A | |
| Pyrene SCHEMBL8821795 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAMAPK1KMT2A | |
| Naphthalene SCHEMBL8651713 | 0.80 | TSHR (0.44) | S1PR2S1PR1S1PR3ALDH1A1MEN1 | |
| Pyrogallol SCHEMBL2882287 | 0.79 | ALDH1A1 (0.47) | S1PR2S1PR1S1PR3EPHX2ALDH1A1 | |
| SCHEMBL304724 | 0.79 | FAAH (0.56) | EPHX2FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |