SCHEMBL9601583

SCHEMBL9601583

OCC1COc2c(ccc(F)c2F)N1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.35
CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433970 1.00 AR (0.35) ARCREBBP
SCHEMBL10434361 0.86 AR (0.36) AR
SCHEMBL25374011 0.81 AR (0.36) AR
SCHEMBL5530352 0.78 NLRP3 (0.35) AR
SCHEMBL2330720 0.76 AR (0.45) AR
SCHEMBL3343457 0.76 AR (0.45) AR
SCHEMBL8979369 0.76 AR (0.45) AR
SCHEMBL27642723 0.72 CREBBP (0.39) CREBBP
SCHEMBL24776144 0.72 GAA (0.37) CREBBP
SCHEMBL3219489 0.72 GAA (0.37) CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0206283-B1 OPTICALLY ACTIVE PYRIDOBENZOXAZINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-01-27 EP disclosed
US-5142046-A Optically active pyridobenzoxazine derivatives and intermediates thereof DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-08-25 US disclosed
US-5053407-A OPTICALLY ACTIVE PYRIDOBENZOXAZINE DERIVATIVES AND ANTI-MICROBIAL USE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1991-10-01 US disclosed
US-4985557-A OFLOXACIN INTERMEDIATE DAIICHI SEIYAKU CO., LTD. (JP) 1991-01-15 US disclosed
EP-0206283-A2 Optically active pyridobenzoxazine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1986-12-30 EP disclosed