SCHEMBL8979466

SCHEMBL8979466

C=Cc1cccc([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c1.C[NH+](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979443 0.92 TP53 (0.35) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL8979449 0.90 TP53 (0.35) TP53TDP1ALDH1A1TSHRPTGS2
Trimethylammonium SCHEMBL8979481 0.89 TP53 (0.41) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL8979464 0.85 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL8979448 0.77 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL577874 0.76
SCHEMBL8979446 0.74 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL8979560 0.74
SCHEMBL7455798 0.72
Trimethylammonium SCHEMBL8979528 0.70 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710663-A1 Boron-containing compound, its polymer, catalyst comprising the polymer and metallocene compound, and process for producing polyolefin Japan Polyolefins Co., Ltd. (JP) 1996-05-08 EP disclosed