Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979498 | 0.81 | MAPT (0.47) | KMT2AMEN1KDM4ELMNAHPGD | |
| SCHEMBL5520431 | 0.79 | MEN1 (0.49) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL8979487 | 0.78 | FPR1 (0.48) | KMT2AMEN1KDM4ELMNAALOX12 | |
| SCHEMBL8560596 | 0.77 | LPAR1 (0.47) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL8566775 | 0.77 | LPAR1 (0.47) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL8567301 | 0.77 | LPAR1 (0.47) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL6993599 | 0.76 | KMT2A (0.55) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL8564979 | 0.75 | GAA (0.45) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL8557914 | 0.75 | KMT2A (0.45) | KMT2AMEN1RAB9AKDM4ELMNA | |
| SCHEMBL8557908 | 0.75 | KMT2A (0.45) | KMT2AMEN1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710725-A1 | Production of optically active compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |