Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.43 |
| ▸ | FES | P07332 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979485 | 0.81 | NFE2L2 (0.43) | MAPTLMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL14254903 | 0.79 | TSHR (0.68) | MAPTLMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL6993599 | 0.77 | KMT2A (0.55) | MAPTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8979503 | 0.77 | ALDH1A1 (0.51) | MAPTLMNAHPGDSMN1; SMN2TSHR | |
| SCHEMBL8567550 | 0.75 | KDM4E (0.46) | MAPTLMNAHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL5226002 | 0.75 | TDP1 (0.54) | MAPTLMNANPC1KDM4EGAA | |
| SCHEMBL8567545 | 0.73 | MAPT (0.42) | MAPTLMNAHPGDSMN1; SMN2TSHR | |
| SCHEMBL17084899 | 0.72 | TRIM24 (0.51) | MAPTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL30981444 | 0.72 | TRIM24 (0.51) | MAPTLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL145083 | 0.71 | CYP1A2 (0.76) | MAPTHPGDTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710725-A1 | Production of optically active compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |