Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979482 | 0.82 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL8979508 | 0.74 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL8979493 | 0.74 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL2110039 | 0.74 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL8557762 | 0.74 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL8979601 | 0.74 | CYP11B1 (0.33) | ALOX5 | |
| SCHEMBL8979497 | 0.70 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL8979500 | 0.66 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL8979548 | 0.66 | TRIM24 (0.39) | ALOX5 | |
| SCHEMBL8979542 | 0.64 | TRPV1 (0.36) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |