Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979508 | 0.82 | ALOX5 (0.46) | TRIM24GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL8979491 | 0.80 | TRIM24 (0.36) | TRIM24CYP11B1CYP11B2TRPV1 | |
| SCHEMBL8979490 | 0.78 | ATAD2 (0.42) | ALDH1A1GAACYP11B1CYP11B2 | |
| SCHEMBL8979522 | 0.77 | TRPV1 (0.36) | TRIM24CYP11B1CYP11B2TRPV1 | |
| SCHEMBL2108075 | 0.74 | TRIM24 (0.36) | TRIM24ALDH1A1GAAGABRG2GABRB3 | |
| SCHEMBL8979554 | 0.74 | TRIM24 (0.38) | TRIM24ALDH1A1GAAGABRG2GABRB3 | |
| SCHEMBL9271757 | 0.72 | ALOX5 (0.41) | TRIM24ALDH1A1GAAGABRG2GABRB3 | |
| SCHEMBL9098383 | 0.71 | ALOX5 (0.51) | ALDH1A1GAAGABRG2GABRB3GABRA5 | |
| SCHEMBL8979482 | 0.71 | ALOX5 (0.34) | TRIM24CYP11B1CYP11B2ALOX5 | |
| SCHEMBL9098432 | 0.71 | ALOX5 (0.42) | TRIM24ALDH1A1GAAGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |