Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 6/20 | 0.60 |
| ▸ | MMP3 | P08254 | 11/20 | 0.45 |
| ▸ | MMP1 | P03956 | 9/20 | 0.45 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP7 | P09237 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979676 | 1.00 | BIRC2 (0.60) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL8979692 | 0.90 | REN (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL6297375 | 0.90 | REN (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL14490676 | 0.85 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL279450 | 0.85 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL279122 | 0.85 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL12601775 | 0.85 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL6292987 | 0.85 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| Actinonin SCHEMBL123273 | 0.85 | BIRC2 (0.56) | BIRC2MMP3MMP1MMP2MMP7 | |
| SCHEMBL6294118 | 0.82 | BIRC2 (0.55) | BIRC2MMP3MMP1MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474553-B1 | Actinonin derivatives | ZAIDAN HOJIN BISEIBUTSU (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0474553-A1 | Actinonin derivatives | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1992-03-11 | — | — | EP | claimed |
| EP-0474553-B1 | Actinonin derivatives | ZAIDAN HOJIN BISEIBUTSU (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5206384-A | Enzyme inhibitors | ZAIDAN HOJIN BISEIBUTSU KAGAKU KAI (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0474553-A1 | Actinonin derivatives | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1992-03-11 | — | — | EP | disclosed |