Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979807 | 0.92 | BRS3 (0.47) | AGTR1AGTR2LTB4R2BRS3 | |
| SCHEMBL8801575 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8979827 | 0.88 | AGTR1 (0.44) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8802179 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8979778 | 0.87 | AGTR1 (0.45) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8979791 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8979758 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8979872 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8979887 | 0.85 | AGTR1 (0.45) | AGTR1AGTR2BDKRB1LTB4R2ACHE | |
| SCHEMBL8673612 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2BDKRB1LTB4R2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |