Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538569 | 0.92 | AGTR1 (0.51) | ACHEAGTR1AGTR2 | |
| SCHEMBL9538974 | 0.91 | ACHE (0.49) | ACHEAGTR1AGTR2 | |
| SCHEMBL8979930 | 0.91 | AGTR1 (0.51) | ACHEAGTR1AGTR2 | |
| SCHEMBL8979861 | 0.89 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8979751 | 0.88 | ACHE (0.45) | ACHEAGTR1AGTR2 | |
| SCHEMBL8979767 | 0.83 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8979836 | 0.81 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8979811 | 0.81 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8979830 | 0.79 | LTB4R2 (0.46) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL8979783 | 0.78 | AGTR1 (0.48) | ACHEAGTR1AGTR2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |