SCHEMBL8979835

SCHEMBL8979835

CCCCc1nc(C)nc(OCc2occc2C(=O)OC)c1Cc1ccc(-c2ccccc2C(=O)OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.43
AGTR2 P50052 2/20 0.43
BDKRB1 P46663 1/20 0.41
ACHE P22303 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979824 0.89 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL8979868 0.86 AGT (0.42) AGTR1AGTR2
SCHEMBL8979741 0.84 AGTR1 (0.43) AGTR1AGTR2BDKRB1ACHELTB4R2
SCHEMBL8979743 0.83 AGTR1 (0.52) AGTR1AGTR2BDKRB1ACHELTB4R2
SCHEMBL8979805 0.82 AGTR1 (0.50) AGTR1AGTR2BDKRB1ACHELTB4R2
SCHEMBL8979769 0.79 AGTR1 (0.47) AGTR1AGTR2ACHELTB4R2
SCHEMBL8979894 0.78 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL8979825 0.78
SCHEMBL8979911 0.78 AGTR1 (0.46) AGTR1AGTR2ACHELTB4R2
SCHEMBL8979880 0.76 AGTR1 (0.49) AGTR1AGTR2ACHELTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
EP-0562731-A1 Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-09-29 EP claimed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP claimed
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5565464-A Compounds having angiotensine II antagonistic activity ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) 1996-10-15 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
EP-0562731-A1 Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-09-29 EP disclosed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP disclosed
US-4985065-A Tetrazolinone herbicides FMC CORPORATION (US) 1991-01-15 US disclosed
US-4898606-A Phosphorylaminophenyltriazolinone herbicides FMC CORPORATION (US) 1990-02-06 US disclosed