Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979769 | 0.95 | AGTR1 (0.47) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8979805 | 0.89 | AGTR1 (0.50) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8979743 | 0.88 | AGTR1 (0.52) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8979906 | 0.83 | AGTR1 (0.44) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL9286819 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8979841 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8979764 | 0.80 | AGTR1 (0.45) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8979891 | 0.79 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8979835 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8979741 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2ACHELTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |
| WO-1993003018-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1993-02-18 | — | — | WO | disclosed |