Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926031 | 0.66 | CRBN (0.48) | TSHRNPSR1ALDH1A1CRBN | |
| SCHEMBL288567 | 0.66 | ALDH1A1 (0.44) | GAAHPGDMAPK1ALDH1A1CRBN | |
| Ammonia Solution, Strong SCHEMBL27683456 | 0.64 | ALDH1A1 (0.42) | GAAHPGDMAPK1ALDH1A1CRBN | |
| SCHEMBL29044524 | 0.64 | ALDH1A1 (0.42) | GAAHPGDMAPK1ALDH1A1CRBN | |
| Methane SCHEMBL27514434 | 0.64 | ALDH1A1 (0.42) | GAAHPGDMAPK1ALDH1A1CRBN | |
| SCHEMBL4269218 | 0.63 | GAA (0.38) | GAAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL17651928 | 0.63 | ALDH1A1 (0.46) | GAAHPGDMAPK1ALDH1A1CRBN | |
| SCHEMBL8559041 | 0.62 | ALDH1A1 (0.37) | ALDH1A1CRBN | |
| SCHEMBL10464804 | 0.62 | — | — | |
| SCHEMBL9406800 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500314-A1 | Process for preparing graft copolymers of polyglutarimides and aromatic polyesters | ROHM AND HAAS COMPANY (US) | 1992-08-26 | — | — | EP | claimed |
| EP-0404346-A1 | Polyamide, polyglutarimide and impact modifier blends | ROHM AND HAAS COMPANY (US) | 1990-12-27 | — | — | EP | claimed |
| US-5585423-A | POLYGLUTARIMIDE SHEETS, FILMS OR MOLDINGS CONTAINING HINDERED AMINE AND BENZOTRIAZOLE PHOTOSTABILIZERS | ROHM AND HAAS COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0404311-A1 | Ultraviolet resistant glutarimide polymers | ROHM AND HAAS COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404346-A1 | Polyamide, polyglutarimide and impact modifier blends | ROHM AND HAAS COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |