Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.53 |
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS1 | P29475 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 9/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980070 | 0.90 | NOS2 (0.55) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL5662514 | 0.88 | NOS2 (0.69) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11084434 | 0.87 | NOS2 (0.68) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL8443007 | 0.84 | NOS2 (0.51) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL8980095 | 0.84 | NOS2 (0.51) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL10921896 | 0.83 | NOS2 (0.55) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL2998260 | 0.83 | NOS2 (0.76) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL8980044 | 0.80 | CYP1A2 (0.48) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL6439514 | 0.78 | NOS2 (0.67) | NOS2NOS3NOS1CYP1A2CYP2D6 | |
| SCHEMBL9526853 | 0.78 | NOS2 (0.67) | NOS2NOS3NOS1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585722-B1 | Benzimidazole derivatives as antimicrobal agent against Campylobacter pylon | EISAI CO LTD (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0585722-A1 | Benzimidazole derivatives as antimicrobal agent against Campylobacter pylon | Eisai Co., Ltd. (JP) | 1994-03-09 | — | — | EP | disclosed |