Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 5/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980071 | 0.90 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8443009 | 0.84 | CYP1A2 (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8980098 | 0.83 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10713639 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8980114 | 0.83 | RAB9A (0.55) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8980045 | 0.80 | NOS2 (0.53) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9834850 | 0.78 | CYP3A4 (0.52) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3911587 | 0.78 | CYP1A2 (0.63) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8130091 | 0.78 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10335251 | 0.77 | CYP1A2 (0.64) | CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585722-B1 | Benzimidazole derivatives as antimicrobal agent against Campylobacter pylon | EISAI CO LTD (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0585722-A1 | Benzimidazole derivatives as antimicrobal agent against Campylobacter pylon | Eisai Co., Ltd. (JP) | 1994-03-09 | — | — | EP | disclosed |