Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980116 | 0.98 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL1999871 | 0.98 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL27646997 | 0.85 | CACNA1B (0.46) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL28902096 | 0.84 | L3MBTL1 (0.52) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL23270918 | 0.82 | NAAA (0.50) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL17675658 | 0.82 | NAAA (0.51) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL23270910 | 0.81 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL2681050 | 0.81 | EPHX1 (0.47) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL872809 | 0.81 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL18933032 | 0.81 | NAAA (0.49) | CYP2C19NAAAHTTCYP19A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | claimed |
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0663382-A1 | Process for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |