SCHEMBL8980212

SCHEMBL8980212

CC(C(=O)O)c1ccc2scnc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.49
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
OGA O60502 2/20 0.43
AKR1C3 P42330 8/20 0.42
AKR1C2 P52895 8/20 0.42
PTGS2 P35354 5/20 0.42
PTGS1 P23219 3/20 0.42
CDC42 P60953 1/20 0.42
RAC1 P63000 1/20 0.42
CYP1A2 P05177 1/20 0.42
TSHR P16473 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
APP P05067 1/20 0.41
MAOA P21397 1/20 0.41
ADRA1A P35348 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418266 0.88 NPC1 (0.55) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL7234547 0.82 FFAR1 (0.47) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL17541608 0.80 FFAR1 (0.44) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL12026663 0.80 ALDH1A1 (0.45) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL24617876 0.77 OGA (0.43) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL21123818 0.77 OGA (0.43) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL30644654 0.77 OGA (0.43) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL17541540 0.77 OGA (0.43) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL23510778 0.77 OGA (0.43) FFAR1KDM4ENPC1RAB9AHKDC1
SCHEMBL2041345 0.77 OGA (0.43) FFAR1OGAHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed
EP-0097720-B1 PROCESS FOR PREPARING SILVER HALIDE EMULSION KONICA CORPORATION (JP) 1986-11-26 EP disclosed
EP-0097720-A1 PROCESS FOR PREPARING SILVER HALIDE EMULSION KONICA CORPORATION (JP) 1984-01-11 EP disclosed